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BROMHEXIN - Medico

Pharmaceutical Form : Tab
Packing : 20tab
Composition : Bromhexin HCl 8 mg. / Tab.
Indications:

Composition :
Each tablet contains :  8 mg.  Bromhexine HCl  .
Each 5 ml of syrup contains :  4 mg. Bromhexine HCl  
Properties  :
- Bromhexine  HCl   is  considered  a  mucolytic   agent  used   for  the  treatment  of  Respiratory  disorders   associated   with   the    presence   mucoviscidosis  ,   as   some refrences    speak   about   the   effect    of   Bromhexine    in   diluting   the    mucosa secretions . Moreover ,  it  also  stimulates  lacrimal  secretion of sjogren’s  syndrome , and  accelerates   the   antibiotics   penetration  in   the   inflammatories  of  mucosa .
Bromhexine  is  rapidly  absorbed  from  gastro intestinal tract , and about 90% of the dose is  excreted  in the urine mainly as metabolites .
The half life of its about 6.5 hours .
Indications :
Bromhexin is used for the treatment of : -   Bacterial  infections  of   the  respiratory   system  associated  with  heavy   viscous sputum  especially :
    * Chronic   and   acute   bronchitis   .
    * Allergic  bronchitis especially bronchial asthma associated with viscous sputum .
    * Chronic obstructive  pneumonia .
    *  Bronchiectasis .
-   May be used in lesions which associated  with xeromucosa in Reiter -Sjogren‘s Syndrome .
Side effects :
* Rarely some  gastro  intestinal  disorders such as  nausea  and vomiting may occur .
* Transient rises in the serum amino transferase .
Precautions :
* this medicine Should be used carefully ( especially  in parenteral use ) in cases of anergy of mucus elimination mechanisms ( as in cases of coma and anesthesia ) .
* Should be used with care in patients with impaired renal and hepatic function , also In patients with a history of peptic ulceration .
Drug interactions :
* Bromhexin should not be used with medicine wich has an atropinic effects .
* Should  be  used  during  pregnancy and nursing period as physician  prescriptions .
Usage & Administration :
* Adults  :  ( 1 -2 )  spoonful   or   ( 1 - 2 )  tablets   ( 3 - 4)  times   daily  as  severity of clinical case .
* Children over 5 years :  one teaspoonful ( 5 ml ) four times daily .
* Children less than 5 years : 1/2 teaspoonful (2.5 ml )three  times daily .
Packing :
Bromhexin syrup : Bottle ( 100 ml )               * Bromhexin tablets : 20 tablets / box .